PK/PD Animal Models & CRO Services

Biotrofix is expert in pharmacokinetic and pharmacodynamic (PK/PD) studies, especially as they involve the nervous or vascular systems. Biotrofix can administer test therapeutic agents into rodents via any route, including systemic (oral, intravenous, subcutaneous, intraperitoneal, etc.), as well as directly into the central nervous system (intraventricular, intracisternal, intrathecal, etc.). This can be done by single or repeated administration, or continuously using a subcutaneously-implanted infusion pump. Moreover, Biotrofix is capable of rapid fluid and tissue sampling, including blood, brain, CSF, spinal cord, and other tissues.